MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof of formula (I), including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treatin...

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Bibliographic Details
Main Authors BINCH, HAYLEY, FANNING, LEV T.D, PIERCE, ALBERT, GROOTENHUIS, PETER D.J
Format Patent
LanguageEnglish
French
Published 10.05.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof of formula (I), including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators. L'invention concerne des modulateurs de transporteurs de cassette de liaison à l'ATP (= ABC =) ou de leurs fragments de formule (I), y compris le régulateur de conductance transmembranaire de fibrose cystique, leurs compositions et des procédés y étant associés. La présente invention concerne également des procédés de traitement de maladies utilisant de tels modulateurs de régulateur de conductance transmembranaire de fibrose cystique.
Bibliography:Application Number: CA20082709301