DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-A]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES

Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

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Bibliographic Details
Main Authors BENTZIEN, JOERG MARTIN, HEIM-RIETHER, ALEXANDER, YU, HUI, BRUNETTE, STEVEN RICHARD, TSCHANTZ, MATT AARON, GAO, DONGHONG A, MCKIBBEN, BRYAN, MOSS, NEIL, LAWLOR, MICHAEL DAVID, CHEN, ZHIDONG, LIU, WEIMIN, MILLER, CRAIG ANDREW, HORAN, JOSHUA COURTNEY, XIONG, ZHAOMING, COGAN, DEREK, YU, YANG, BARBOSA, ANTONIO JOSE DEL MORAL, KOWALSKI, JENNIFER A, LEMIEUX, RENE M
Format Patent
LanguageEnglish
French
Published 04.06.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
Bibliography:Application Number: CA20082705583