RENIN INHIBITORS

The present invention relates to acyclic amino amides of formula (I). These compounds are renin inhibitors of a non-peptidic nature and of low molecular weight. The invention further relates to processes for the preparation of these compounds, pharmaceutical compositions containing them, as well as...

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Bibliographic Details
Main Authors CHEN, AUSTIN CHIH-YU, DUBE, DANIEL, MCKAY, DANIEL J
Format Patent
LanguageEnglish
French
Published 12.02.2009
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to acyclic amino amides of formula (I). These compounds are renin inhibitors of a non-peptidic nature and of low molecular weight. The invention further relates to processes for the preparation of these compounds, pharmaceutical compositions containing them, as well as their use and method of treatment of cardiovascular events and renal insufficiency.
Bibliography:Application Number: CA20082695461