NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS

The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds a...

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Bibliographic Details
Main Authors ROBERT, PHILIPPE, LECOMTE, JEANNE-MARIE, JIVANI, JIGNESH KANTILAL, CAPET, MARC, PILLAI, MUTHUKUMARAN NATARAJAN, PANCHAL, BHAVESH MOHANBHAI, LEVOIN, NICOLAS, SAMANTA, BISWAJIT, BERREBI-BERTRAND, ISABELLE, ARADHYE, JAYRAJ DILIPBHAI, PAL, RANJAN KUMAR, THENNATI, RAJAMANNAR, SCHWARTZ, JEANARLES
Format Patent
LanguageEnglish
French
Published 18.12.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and use of these compounds for treatment/prevention of immune medi-ated diseases and conditions or inflammatory diseases and conditions.
Bibliography:Application Number: CA20082693126