METHODS AND COMPOSITIONS FOR INHIBITING CD32B EXPRESSING CELLS

The present invention relates to immunoglobulins that bind Fc.kappa.RIIb+ cells and coengage the antigen on the cell's surface and an Fc.gamma.RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins. La présente invention concerne des immunoglobu...

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Bibliographic Details
Main Authors KARKI, SHER BAHADUR, MOORE, GREGORY, VOSTIAR, IGOR, LAZAR, GREGORY ALAN, CHU, SEUNG YUP, DESJARLAIS, JOHN R
Format Patent
LanguageEnglish
French
Published 05.01.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to immunoglobulins that bind Fc.kappa.RIIb+ cells and coengage the antigen on the cell's surface and an Fc.gamma.RIIb on the cell's surface, methods for their generation, and methods for using the immunoglobulins. La présente invention concerne des immunoglobulines de liaison aux cellules Fc?Rllb+ et d'engagement conjoint avec l'antigène sur la surface de la cellule et un Fc?Rllb sur la surface de la cellule, ainsi que leurs procédés de génération, et des procédés d'utilisation des immunoglobulines.
Bibliography:Application Number: CA20082693053