SUBSTITUTED 2- [2- (PHENYL) ETHYLAMINO] ALKANEAMIDE DERIVATIVES AND THEIR USE AS SODIUM AND/OR CALCIUM CHANNEL MODULATORS

Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I ) wherein X, Y, Z, R, R1, R2, R3, R'3, R4, R5, R6, R7 have the meanings defi ned in the specification and pharmaceutically acceptable salts thereof, phar maceutical compositions containing them as active ingredient and th...

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Bibliographic Details
Main Authors IZZO, EMANUELA, SABIDO-DAVID, CIBELE, RESTIVO, ALESSANDRA, COLOMBO, ELENA, FRANCISCONI, SIMONA, MELLONI, PIERO
Format Patent
LanguageEnglish
French
Published 18.12.2008
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I ) wherein X, Y, Z, R, R1, R2, R3, R'3, R4, R5, R6, R7 have the meanings defi ned in the specification and pharmaceutically acceptable salts thereof, phar maceutical compositions containing them as active ingredient and their use a s sodium and/or calcium channel modulators useful in preventing, alleviating and curing a wide range of pathologies, including, but not limited to, neur ological, cognitive, psychiatric, inflammatory, urogenital and gastrointesti nal diseases, where the above mechanisms have been described as playing a pa thological role.
Bibliography:Application Number: CA20082689561