1,(3,)5-SUBSTITUTED IMIDAZOLES, THEIR USE IN THE TREATMENT OF HYPERTENSION AND METHODS FOR THEIR PREPARATION

The present invention provides novel 1,5 and 1,3,5-substituted imidazole compounds in hydrophilic or lipophilic form, which are useful as angiotensin II ATI receptor antagonists suitable for transdermal delivery. The inventio n also provides pharmaceutical compositions containing such compounds, pro...

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Bibliographic Details
Main Authors MATSOUKAS, JOHN, VLAXAKOS, DIMITRIOS, MARAGOUDAKIS, MICHAEL
Format Patent
LanguageEnglish
French
Published 27.11.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention provides novel 1,5 and 1,3,5-substituted imidazole compounds in hydrophilic or lipophilic form, which are useful as angiotensin II ATI receptor antagonists suitable for transdermal delivery. The inventio n also provides pharmaceutical compositions containing such compounds, proce sses and intermediates for preparing compounds and their use in methods of t reating hypertension and cardiovascular diseases.
Bibliography:Application Number: CA20082687975