PROCESS FOR THE PRODUCTION OF PYRAZOLES

A process for the production of a compound of formula (I), which comprises a) reacting a compound of formula (II), wherein R1 and R2 are both independently C1-C6 alkyl, with methylhydrazine in the presence of water and a water-immiscible organic solvent being inert in saponification reactions, to fo...

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Bibliographic Details
Main Authors GIORDANO, FANNY, WANG, LINHUA, VETTIGER, THOMAS, WISS, JUERG GUSTAV
Format Patent
LanguageEnglish
French
Published 30.06.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for the production of a compound of formula (I), which comprises a) reacting a compound of formula (II), wherein R1 and R2 are both independently C1-C6 alkyl, with methylhydrazine in the presence of water and a water-immiscible organic solvent being inert in saponification reactions, to form a compound of formula (III) wherein R1 is as defined for formula (II) and b) saponifying that compound in sit.upsilon. leading to the formation of the compound of formula (I) by b1) adding a base to form the anion of the compound of formula (I) and then adding an; acid to form the compound of formula (I); or b2) adding an acid to form the compound of formula (I).
Bibliography:Application Number: CA20082687176