NOVEL PYRROLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

A compound represented by the general formula (I): (I) [wherein R1, R2, R 3, Z1, Z2, Ra, Rb, q, A, and n are as defined in the description], a pharmac eutically acceptable salt of the compound, or a solvate of either. These are useful as a P2X3 and/or P2X2/3 antagonist.

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Bibliographic Details
Main Authors KAMEYAMA, TAKAYUKI, KAI, HIROYUKI, SHINOHARA, SHUNJI
Format Patent
LanguageEnglish
French
Published 09.10.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound represented by the general formula (I): (I) [wherein R1, R2, R 3, Z1, Z2, Ra, Rb, q, A, and n are as defined in the description], a pharmac eutically acceptable salt of the compound, or a solvate of either. These are useful as a P2X3 and/or P2X2/3 antagonist.
Bibliography:Application Number: CA20082682473