PEGYLATED A.BETA. FAB

A method to treat conditions associated with Aß peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human Aß peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached...

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Bibliographic Details
Main Authors CHOW, CHI-KIN, KUCHIBHOTLA, UMA, HANSEN, RYAN JOHN, LU, JIRONG, MCDONNELL, PETER COLON, BALES, KELLY RENEE, BUMOL, THOMAS FRANK, DEMATTOS, RONALD BRADLEY
Format Patent
LanguageEnglish
French
Published 30.12.2014
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:A method to treat conditions associated with Aß peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human Aß peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.
Bibliography:Application Number: CA20082675847