CRYSTALLINE D-ISOGLUTAMYL-D-TRYPTOPHAN AND THE MONO AMMONIUMSALT OF D-ISOGLUTAMYL-D-TRYPTOPHAN
A process for making pure crystalline D-isoglutamyl-D-tryptophan is provi ded which includes the step of deprotecting essentially pure N-tert-butoxyca rbonyl-D- isoglutamyl-D-tryptophan or its diester to yield essentially pure D-isoglutamyl-D- tryptophan. A process is also provided for the preparati...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French |
Published |
05.06.2008
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Subjects | |
Online Access | Get full text |
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Summary: | A process for making pure crystalline D-isoglutamyl-D-tryptophan is provi ded which includes the step of deprotecting essentially pure N-tert-butoxyca rbonyl-D- isoglutamyl-D-tryptophan or its diester to yield essentially pure D-isoglutamyl-D- tryptophan. A process is also provided for the preparation of pure mono ammonium salt of D-isoglutamyl-D-tryptophan from essentially pu re N-tert-butoxycarbonyl-D- isoglutamyl-D-tryptophan. D-isoglutamyl-D-trypto phan, ammonium salt (1 :1) is a stable pharmaceutical solid. |
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Bibliography: | Application Number: CA20072672369 |