ACAT INHIBITORS AND THEIR USE IN THE PREVENTION OR TREATMENTOF FIBROSIS

The present invention relates to the use of ACAT inhibitors, {e.g. F-1394 , Avasimibe (CI-1011), Pactimibe (CS505), Efluimibe (F12511), Eldacimibe, NT E 122, AS-183, KW-3033, E5324, FY087, FCE27677, CI-976, K-604, TEI6522, Octi mibate, FR179254, and S 58-035, or mixtures thereof), compositions compr...

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Bibliographic Details
Main Authors JIA, XIHUA, BRANICKY, ROBYN S, HEKIMI, SIEGFRIED, HIHI, ABDELMADJID K
Format Patent
LanguageEnglish
French
Published 22.05.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to the use of ACAT inhibitors, {e.g. F-1394 , Avasimibe (CI-1011), Pactimibe (CS505), Efluimibe (F12511), Eldacimibe, NT E 122, AS-183, KW-3033, E5324, FY087, FCE27677, CI-976, K-604, TEI6522, Octi mibate, FR179254, and S 58-035, or mixtures thereof), compositions comprisin g the same, and methods for preventing or treating fibrosis, for preventing or reducing collagen deposition in a tissue, and in the prevention and reduc tion of excessive fibrous connective tissue
Bibliography:Application Number: CA20072669123