MELT-PROCESSED IMATINIB DOSAGE FORM

The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, ( b) at least one polymeric binder, and (c) at least one pharmaceutically acce ptable non-ionic surfactant. The invention provides imatinib dosage forms...

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Bibliographic Details
Main Authors BREITENBACH, JOERG, ALTENBURGER, RALF, KNOBLOCH, MARTIN, LOGGIA, NICOLETTA, WESTEDT, ULRICH, HACH, HARALD, OGORKA, JOERG, STEIGER, NORBERT
Format Patent
LanguageEnglish
French
Published 15.05.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, ( b) at least one polymeric binder, and (c) at least one pharmaceutically acce ptable non-ionic surfactant. The invention provides imatinib dosage forms wi th high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an ess entially pH-independent fashion, and extended release imatinib dosage forms.
Bibliography:Application Number: CA20072668775