ENANTIOMERIC FUSED-PYRIDINONE COMPOUNDS WITH ANTIBACTERIAL ACTIVITY
Novel compounds in enantiomeric excess that are inhibitors of bacterial methionyl synthetase (MetRS) are disclosed. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, and in particular their use in therapy for Clostridium difficile infection. L'in...
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Main Authors | , , , , |
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Format | Patent |
Language | English French |
Published |
23.12.2014
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Subjects | |
Online Access | Get full text |
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Summary: | Novel compounds in enantiomeric excess that are inhibitors of bacterial methionyl synthetase (MetRS) are disclosed. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, and in particular their use in therapy for Clostridium difficile infection.
L'invention concerne de nouveaux composés en excès énantiomère étant des inhibiteurs de la méthionyl synthétase bactérienne (MetRS). L'invention concerne également des procédés de préparation de ces composés et leur utilisation en thérapie en tant qu'agents antibactériens, notamment dans la thérapie d'infections par clostridium difficile. |
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Bibliography: | Application Number: CA20072664588 |