AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM

Disclosed are compounds of formula (I) wherein Z1 is -CH2- or -C(O)-, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5 , and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclose...

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Bibliographic Details
Main Authors SMITH, ELIZABETH M, MCKITTRICK, BRIAN, BURNETT, DUANE A, KNUTSON, CHAD E, BENNETT, CHAD E
Format Patent
LanguageEnglish
French
Published 20.03.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds of formula (I) wherein Z1 is -CH2- or -C(O)-, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5 , and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclosed are methods of treating pain using a compound of formula (I).
Bibliography:Application Number: CA20072663947