SYSTEM AND METHOD FOR CO-REGISTERING MULTI-CHANNEL IMAGES OFA TISSUE MICRO ARRAY

A system and methods for co-registering multi-channel images of a tissue micro array, comprising the steps of, providing a biological material on a s ubstrate; applying one or more molecular probes, adapted to provide fluoresc ent molecular markers, to the biological material; obtaining a first digi...

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Bibliographic Details
Main Authors CAN, ALI, CLINE, HARVEY ELLIS
Format Patent
LanguageEnglish
French
Published 21.02.2008
Subjects
CALCULATING
COMPUTING
COUNTING
IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
PHYSICS
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Summary:A system and methods for co-registering multi-channel images of a tissue micro array, comprising the steps of, providing a biological material on a s ubstrate; applying one or more molecular probes, adapted to provide fluoresc ent molecular markers, to the biological material; obtaining a first digital image of the biological material and the fluorescent molecular markers; app lying a morphological stain to the biological material; obtaining a second d igital image of the biological material, computing information common to the first and second images; and co-registering the second image with the first image based on one or more registration metrics.
Bibliography:Application Number: CA20072658827