THERAPEUTIC COMPOUNDS

The invention relates to a method of improving oral drug absorption of ad enosine analogues by the use of 2-methoxy adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further relates to compoun ds that are pro-drugs of adenosine receptor agonists, and to their use as...

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Bibliographic Details
Main Author SAVORY, EDWARD DANIEL
Format Patent
LanguageEnglish
French
Published 03.01.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a method of improving oral drug absorption of ad enosine analogues by the use of 2-methoxy adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further relates to compoun ds that are pro-drugs of adenosine receptor agonists, and to their use as th erapeutic compounds, in particular as analgesic or anti-inflammatory compoun ds, or as disease modifying antirheumatic drugs (DMARDs), and to methods of preventing, treating or ameliorating pain or inflammation using these compou nds.
Bibliography:Application Number: CA20072654371