PYRAZOLOPYRIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS USEFUL AS KINASE ENZYMES MODULATORS

• Main Authors: WHITE, RYAN, DIMAURO, ERIN F, TOMLINSON, SUSAN A, HAO, XIAOLIN, MASSE, CRAIG E, BUCHANAN, JOHN L, FU, JIASHENG, ZHU, XIAOTIAN, JIAO, XIANYUN, KAYSER, FRANK, CARDOZO, MARIO G, BUCKNER, WILLIAM H, KOPECKY, DAVID J
• Format: Patent
• Language: English; French
• Published: 01.03.2007
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to compounds of Formula (I) or a stereomer, a tautomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereo f, pharmaceutical formulations containing the compounds, methods of treatments using the compounds, for example, protein tyrosine kinase-associated disorde rs such as immunologic and oncologic disorders and methods of preparing medicaments comprising the compounds.