ANTINEOPLASTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF

• Main Authors: VERA ALVAREZ, ROBERTO, MAZOLA REYES, YULIET, PEREA RODRIGUEZ, SILVIO ERNESTO, DE LA NUEZ VEULENS, ANIA, MUSACCHIO LASA, ALEXIS, UBIETA GOMEZ, RAIMUNDO, ACEVEDO CASTRO, BORIS ERNESTO, RODRIGUEZ FERNANDEZ, ROLANDO EDUARDO
• Format: Patent
• Language: English; French
• Published: 09.12.2014
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention relates to chemical compounds which are obtained by means of in silico molecular modelling and which have a structure that can be used to block phosphorylation by interacting said compounds with the phosphorylation domain or the environment thereof in the substrates of the Casein Kinas...