OPTICALLY ACTIVE TETRAHYDRONAPHTHALENE DERIVATIVE

A compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate thereof or a solvate thereof, which shows not only a C5a receptor antagonistic activity but also high activity in the biological availability, as compared to its racemate.

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Bibliographic Details
Main Authors UEDA, NAOKO, SUMICHIKA, HIROSHI, ISHIBUCHI, SEIGO, NAKAMURA, MITSUHARU, SEKIGUCHI, SUMIE, ISHIGE, TAKAYUKI, OHTSUKA, TATSUYUKI
Format Patent
LanguageEnglish
French
Published 10.08.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate thereof or a solvate thereof, which shows not only a C5a receptor antagonistic activity but also high activity in the biological availability, as compared to its racemate.
Bibliography:Application Number: CA20062596993