ANTI-T CELL AND AUTOANTIGEN TREATMENT OF AUTOIMMUNE DISEASE
The invention is directed to a new method for the treatment of new onset Type I diabetes in mammals or for the treatment of pre-Type I diabetic mammals where the method comprises administering (a) anti-T cell therapy to the mammal and administering (b) an autoantigen and optional mucosal antigen com...
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Main Authors | , , , , , |
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Format | Patent |
Language | English French |
Published |
10.08.2006
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Subjects | |
Online Access | Get full text |
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Summary: | The invention is directed to a new method for the treatment of new onset Type I diabetes in mammals or for the treatment of pre-Type I diabetic mammals where the method comprises administering (a) anti-T cell therapy to the mammal and administering (b) an autoantigen and optional mucosal antigen composition, wherein (a) and (b) are administered concurrently or sequentially Exemplified is a treatment using a mixture of anti-CD3 antibodies, a glutamic acid decarboxylase (GAD) autoantigen, and an immunoregulatory cytokine Canme GAD sequences are also disclosed. |
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Bibliography: | Application Number: CA20062596332 |