NUCLEOTIDE ANALOG COMPOSITIONS

The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present inventi on have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention...

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Main Authors MUNGER, JOHN D., JR, LEE, THOMAS T.K, ARIMILLI, MURTY N, SCHULTZE, LISA M, PRISBE, ERNEST J, KELLY, DAPHNE E, MANES, LAWRENCE V
Format Patent
LanguageEnglish
French
Published 23.12.2008
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present inventi on have desirable properties for large scale synthesis of crystalline adefovir dipivoxil or for its formulation into therapeutic dosages. Invention compositions include an anhydrous crystal form of adefovir dipivoxil.
Bibliography:Application Number: CA19982596320