SUBSTITUTED HETEROCYCLES AND METHODS OF USE

Selected compounds of Formula (I) are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases such as cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. R - X - W - A - Y - R...

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Main Authors BELLON, STEVEN, LEE, MATTHEW, CHENG, YUAN, XI, NING, KIM, TAE-SEONG, TASKER, ANDREW, RAINBEAU, ELIZABETH, D'ANGELO, NOEL, SIEGMUND, AARON C, BOOKER, SHON, DOMINGUEZ, CELIA, FELLOWS, INGRID, LIU, LONGBIN
Format Patent
LanguageEnglish
French
Published 09.04.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Selected compounds of Formula (I) are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases such as cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. R - X - W - A - Y - R Formula (I) wherein R is X is O, S, NR2 or CR3R4 W is an substituted or unsubstituted aryl or substituted or unsubstituted 5- or 6- membered heteroaryl.
Bibliography:Application Number: CA20052587642