NOVEL NUCLEOTIDE AND AMINO ACID SEQUENCES, AND ASSAYS AND METHODS OF USE THEREOF FOR DIAGNOSIS OF CARDIAC DISEASE

Novel markers for cardiac disease that are both sensitive and accurate. Thes e markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscl e tissue. The measurement of these markers, alone or in combinati...

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Main Authors KOL, GUY, POLLOCK, SARAH, SHEMESH, RONEN, TOPORIK, AMIR, DAHARY, DVIR, COHEN, YOSSI, NOVIK, AMIT, AYALON-SOFFER, MICHAL, DIBER, ALEXANDER, COJOCARU, GAD S, WALACH, SHIRA, SELLA-TAVOR, OSNAT, LEVINE, ZURIT, SAMEAH-GREENWALD, SHIRLEY
Format Patent
LanguageEnglish
French
Published 04.08.2005
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Summary:Novel markers for cardiac disease that are both sensitive and accurate. Thes e markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues, optionally and preferably including muscl e tissue. The measurement of these markers, alone or in combination, in patien t samples provides information that the diagnostician can correlate with a probable diagnosis of cardiac disease, including pathology and/or damage, including acute and/or chronic damage. The markets of the present invention, alone or in combination, show a high degree of differential detection betwee n cardiac disease states and non-cardiac disease states.
Bibliography:Application Number: CA20052554585