METHOD FOR PRODUCING (3-OXO-2,3-DIHYDRO-1H-ISOINDOL-1-YL)ACETYLGUANIDINE DERIVATIVES

The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of...

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Main Authors RIEKE-ZAPP, JOERG, KLEEMANN, HEINZ-WERNER, HANNA, REDA, SCHUBERT, GERRIT, WU, XIAO-DONG, GOURAUD, YVES, KEIL, JOHANNES, HUANG, BAO-GUO
Format Patent
LanguageEnglish
French
Published 08.01.2013
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Summary:The invention relates to methods for producing (3-oxo-2,3-dihydro-1H-isoindol-1-yl) acetylguanidine derivatives of formula (I) using 3-hydroxy-2,3-dihydro-1 H-isoindol-1-one derivatives or 3-(2-carbamoyl-phenyl) acrylic acid ester derivatives as intermediate stages, to a method for the resolution of racemates and to intermediate products of the inventive method.
Bibliography:Application Number: CA20042548020