MACROCYCLIC CARBOXYLIC ACIDS AND ACYLSULFONAMIDES AS INHIBITORS OF HCV REPLICATION

• Main Authors: KENNEDY, APRIL LAYNE, ANDREWS, STEVEN WADE, WENGLOWSKY, STEVEN MARK, WOODARD, BENJAMIN T, JIANG, YUTONG, MADDURU, MACHENDER R, CONDROSKI, KEVIN RONALD, JOSEY, JOHN ANTHONY, DOHERTY, GEORGE ANDREW, BLATT, LAWRENCE M, STENGEL, PETER JOHN
• Format: Patent
• Language: English; French
• Published: 08.12.2009
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; ORGANIC MACROMOLECULAR COMPOUNDS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The present invention provides compounds of the general formulas I-IX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The present invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of t...