SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE

The present invention relates to tetracyclic pyrimidines or pyridines or pharmaceutically-acceptable salts or derivatives thereof. Also included are methods of use of the tetracyclic pyrimidines or pyridines including use related to treating inflammation, inhibiting T cell activation and proliferati...

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Bibliographic Details
Main Authors SALUSTE, CARL-GUSTAF PIERRE, GHIRON, CHIARA, ZHU, XIAOTIAN, ERMANN, MONIKA, JOHNSTON, DAVID N, NUNES, JOSEPH J
Format Patent
LanguageEnglish
French
Published 10.03.2005
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to tetracyclic pyrimidines or pyridines or pharmaceutically-acceptable salts or derivatives thereof. Also included are methods of use of the tetracyclic pyrimidines or pyridines including use related to treating inflammation, inhibiting T cell activation and proliferation, arthritis, organ transplant, ischemic or reperfusion injury, myocardial infarction, stroke, multiple sclerosis, inflammatory bowel diseas e and many other related disorders in a subject, the methods comprising administering a therapeutically-effective amount a compound as described abo ve to the subject.
Bibliography:Application Number: CA20042536786