CASPASE INHIBITORS CONTAINING ISOXAZOLINE RING

The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same. The isoxazoline derivative corresponds to the compound of formula (I) (s...

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Main Authors KIM, AE-RI, KIM, HO-JUN, OH, YEONG-SOO, LEE, TAE-SOO, KWON, TAE-SIK, MIN, KYEONG-SIK, LEE, KYU-WOONG, LEE, SUN-HWA, SEONG, JEONG HUI, KIM, SOO-HYEON, KIM, MIN-JUNG, KIM, SUNG-SUB, PARK, KI-SOOK, LEE, JAE-HOON, PARK, TAE-KYO, SHIN, HYUN-IK, PARK, HEE-DONG, LEE, SANG-KYUN, KIM, HWA-DONG, HEO, TAE-HO, JANG, YONG-JIN, CHOI, HYEONG-WOOK, PARK, CHEOL-WON, PARK, JUNG-GYU, JEONG, HEE-KYUNG, PARK, MI-JEONG, CHANG, HYE-KYUNG
Format Patent
LanguageEnglish
French
Published 05.07.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to an isoxazoline derivative as an inhibitor against various caspases, a process for preparing the same, and a therapeutic composition for preventing inflammation and apoptosis comprising the same. The isoxazoline derivative corresponds to the compound of formula (I) (see formula I) La présente invention concerne un dérivé isoxazolinique constituant un inhibiteur de diverses caspases, un procédé de préparation de ce dérivé et une composition thérapeutique destinée à prévenir l'inflammation et l'apoptose, cette composition comprenant ledit dérivé.
Bibliography:Application Number: CA20042535711