CRYSTALLINE VAP-1 AND USES THEREOF

The present invention relates to crystalline vascular adhesion protein-1 (VA P- 1) and in particular to methods for the use of structural information of crystalline human VAP-1 for ligand and/or inhibitor identification, design a nd production, as well as screening assays for detection of same. The...

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Main Authors JOHNSON, MARK, SMITH, DAVID, PENTIKAINEN, OLLI, SODERHOLM, ANNU, AIRENNE, TOMI, VIITANEN, LENITA, SALMINEN, TIINA, PIHLAVISTO, MARJO, KIDRON, HEIDI, NYRONEN, TOMMI, NYMALM-REJSTROM, YVONNE
Format Patent
LanguageEnglish
French
Published 02.12.2004
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SEPARATION
SPIRITS
TRANSPORTING
VINEGAR
WINE
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Summary:The present invention relates to crystalline vascular adhesion protein-1 (VA P- 1) and in particular to methods for the use of structural information of crystalline human VAP-1 for ligand and/or inhibitor identification, design a nd production, as well as screening assays for detection of same. The invention further relates to inhibitors identified by the assays according to the present invention.
Bibliography:Application Number: CA20042526675