PARENTERAL FORMULATIONS CONTAINING A RAPAMYCIN HYDROXYESTER
This invention provides cosolvent concentrates containing rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779), a parenterally acceptable solvent, and an antioxidant. Also provided are parenteral formulations which contain aforementioned concentrate, diluent solvent,...
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Main Authors | , , , |
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Format | Patent |
Language | English French |
Published |
23.07.2013
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Subjects | |
Online Access | Get full text |
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Summary: | This invention provides cosolvent concentrates containing rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779), a parenterally acceptable solvent, and an antioxidant. Also provided are parenteral formulations which contain aforementioned concentrate, diluent solvent, and a surfactant and methods for preparing the same.
Cette invention se rapporte à des formulations parentérales contenant de l'ester-42 de rapamycine associé à de l'acide 3-hydroxy-2(hydroxyméthyl)-2-méthylpropionique. |
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Bibliography: | Application Number: CA20032493878 |