METHODS FOR WET GRANULATING AZITHROMYCIN

The present invention relates to a method of forming non-dihydrate azithromycin granules, comprising mixing non-dihydrate azithromycin particle s, with a granulating amount of a granulating liquid, and, optionally, with particles of one or more excipients, to form wet granules which comprise non - d...

Full description

Saved in:
Bibliographic Details
Main Authors JOHNSON, BARBARA ALICE, FERGIONE, MICHAEL BRUCE
Format Patent
LanguageEnglish
French
Published 03.07.2003
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a method of forming non-dihydrate azithromycin granules, comprising mixing non-dihydrate azithromycin particle s, with a granulating amount of a granulating liquid, and, optionally, with particles of one or more excipients, to form wet granules which comprise non - dihydrate azithromycin and the granulating liquid. The granules are then dri ed to remove the granulating liquid. The invention further relates to a pharmaceutical composition comprising granules of a non-dihydrate azithromyc in and at least one pharmaceutically acceptable excipient. The invention also relates to pharmaceutical formulations comprising granules of non-dihydrate azithromycin. The invention further relates to granules of dihydrate azitrhromycin wherein the granules comprises 98% or more dihydrate azithromycin and from about 2% to 0%, total weight, of one or more pharmaceutically acceptable excipients.
Bibliography:Application Number: CA20022470055