CLONAL MYELOMA CELL LINES USEFUL FOR MANUFACTURING PROTEINS IN CHEMICALLY DEFINED MEDIA

• Main Authors: MOORE, GORDON, LEE, CHICHANG, SAVINO, EDWARD, LY, CELIA
• Format: Patent
• Language: English; French
• Published: 26.06.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates to clonal myeloma cell lines that have the ability to grow continuously in chemically defined media. The present invention also relates to the production of proteins in clonal myeloma cell lines and any cell lines derived therefrom. The present invention further relates to methods for identifying cell lines capable of growing in chemical ly defined media. The present invention also relates to business methods where customers are provided with the cells, cell lines, and cell cultures of the present invention.