THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE

• Main Authors: GERLACH, VALERIE L, ZHONG, MEI, CASMAN, STACIE J, ELLERMAN, KAREN, PENA, CAROL E. A, RASTELLI, LUCA, SMITHSON, GLENNDA, GUO, XIAOJIA, EDINGER, SHLOMIT R, SHIMKETS, RICHARD A, SHENOY, SURESH G, LI, LI, ANDERSON, DAVID W, KEKUDA, RAMESH, SPYTEK, KIMBERLY A, VOSS, EDWARD Z, HJALT, TORD, BAUMGARTNER, JASON C, PEYMAN, JOHN A, VERNET, CORINE A. M, CATTERTON, ELINA, PATTURAJAN, MEERA, BOLDOG, FERENC L, TAUPIER, RAYMOND J. JR, GORMAN, LINDA, MILLER, CHARLES E, PADIGARU, MURALIDHARA, CHAPOVAL, ANDREI
• Format: Patent
• Language: English; French
• Published: 09.10.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to novel polypeptides, and the nucleic acids encoding them, having properties related to stimulation of biochemical or physiological responses in a cell, a tissue, an organ or an organism. More particularly, the novel polypeptides are gene products of novel genes, or ar e specified biologically active fragments or derivatives thereof. Methods of u se encompass diagnostic and prognostic assay procedures as well as methods of treating diverse pathological conditions.