COMPOSITIONS FOR DELIVERING BISPHOSPHONATES

There is a need for improved delivery systems for therapeutic agents such as bisphosphonates. The present invention provides compounds and compositions that facilitate the delivery of bisphosphonates to selected biological systems and increase or improve the bioavailability of bisphospohonates. The...

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Bibliographic Details
Main Authors DINH, STEVE, BOYD, MARIA A. P
Format Patent
LanguageEnglish
French
Published 03.05.2011
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is a need for improved delivery systems for therapeutic agents such as bisphosphonates. The present invention provides compounds and compositions that facilitate the delivery of bisphosphonates to selected biological systems and increase or improve the bioavailability of bisphospohonates. The delivery agents of the present invention have the general formulae: (see compound 1)(see compound 2) (see compound 3)(see compound 4) (see compound 5)(see compound 6) (see compound 7)(see compound 8) (see compound 9)(see compound 10) Methods of preparation, administration, and treatment are also disclosed.
Bibliography:Application Number: CA20022438848