ETHANOLATES OF SODIUM-HYDROGEN EXCHANGER TYPE-1 INHIBITOR

The invention relates to ethanolates of the NHE-1 inhibitor, N-(5-cyclopropy l- 1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine, crystalline forms of the ethanolates, methods of preparing the ethalolates, methods of treatment usin g the ethanolates and the mesylate salt of the NHE-1 inhibitor prep...

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Bibliographic Details
Main Authors NORRIS, TIMOTHY, WEEKLY, RODNEY MATTHEW
Format Patent
LanguageEnglish
French
Published 08.08.2002
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to ethanolates of the NHE-1 inhibitor, N-(5-cyclopropy l- 1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine, crystalline forms of the ethanolates, methods of preparing the ethalolates, methods of treatment usin g the ethanolates and the mesylate salt of the NHE-1 inhibitor prepared using the ethanolates.
Bibliography:Application Number: CA20012436539