3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGENC-PROTEINASE INHIBITORS

Compound of formula (I), wherein X is C~1-6 alkylene or C~2-6 alkenylene, ea ch of which is optionally substituted by one or more flluorine atoms; R is aryl or C~3-8 cycloalkyl optionally substituted by one or more fluorine atoms; W is N or CZ; are procollagen C-proteinase (PCP) inhibitors useful in...

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Bibliographic Details
Main Authors FISH, PAUL VINCENT, WHITLOCK, GAVIN ALISTAIR, JAMES, KIM, DATTA, USA
Format Patent
LanguageEnglish
French
Published 27.06.2002
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compound of formula (I), wherein X is C~1-6 alkylene or C~2-6 alkenylene, ea ch of which is optionally substituted by one or more flluorine atoms; R is aryl or C~3-8 cycloalkyl optionally substituted by one or more fluorine atoms; W is N or CZ; are procollagen C-proteinase (PCP) inhibitors useful in treating conditions mediated by PCP.
Bibliography:Application Number: CA20012432643