PREPARATION OF SODIUM-HYDROGEN EXCHANGER TYPE-1 INHIBITORS

This invention relates to methods of preparing sodium-hydrogen exchanger type 1 (NHE-1) inhibitors of formula (I') intermediates of the NHE-1 inhibitors and a new almost colorless form of the NHE-1 inhibitor N-(5-cyclopropyl-1-quinolin- 5-yl-1H-pyrazole-4-carbonyl)-guanidine.

Saved in:
Bibliographic Details
Main Authors LAMBERT, JOHN FRANCIS, NORRIS, TIMOTHY
Format Patent
LanguageEnglish
French
Published 06.06.2002
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:This invention relates to methods of preparing sodium-hydrogen exchanger type 1 (NHE-1) inhibitors of formula (I') intermediates of the NHE-1 inhibitors and a new almost colorless form of the NHE-1 inhibitor N-(5-cyclopropyl-1-quinolin- 5-yl-1H-pyrazole-4-carbonyl)-guanidine.
Bibliography:Application Number: CA20012430061