INDOLE DERIVATIVES AND MEDICAL APPLICATIONS THEREOF

Indole derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof, and pharmaceutical compositions (particularly d opioid receptor agonist) containing the same: (I) wherein R1 is hydrogen, C1-5 alkyl, or the like; R2 is hydrogen, hydroxyl, or the like; R3 is hyd...

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Bibliographic Details
Main Authors MAEDA, MASAYUKI, AOKI, TAKUMI, UENO, SHINYA, SAKAMI, SATOSHI, KAWAI, KOJI
Format Patent
LanguageEnglish
French
Published 30.05.2002
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Indole derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof, and pharmaceutical compositions (particularly d opioid receptor agonist) containing the same: (I) wherein R1 is hydrogen, C1-5 alkyl, or the like; R2 is hydrogen, hydroxyl, or the like; R3 is hydrogen, hydroxyl, or the like; -Z- is a bridge having 2 to 5 carbon atoms; m is an integer of 0 to 3; n is an integer of 0 to 10; R4 and R5 are each fluoro, hydroxyl, or the like; R9 is hydrogen, C1-5 alkyl, or the like; and R10 and R11 may be united to form O- or the like.
Bibliography:Application Number: CA20012427931