MOLECULES FOR DISEASE DETECTION AND TREATMENT

• Main Authors: YAP, PIERRE E, CHEN, ALICE J, DAFFO, ABEL, HILLMAN, JENNIFER L, HARRIS, BERNARD, LIU, TOMMY F, JACKSON, STUART, WRIGHT, RACHEL J, PANZER, SCOTT R, INMAN, REBEKAH R, BRADLEY, DIANA L, AU, ALAN P, DAHL, CHRISTOPHER R, ROHATGI, SAMEER D, DUFOUR, GERARD E, MOMIYAMA, MONIKA G, DAVID, MARIE H, PERALTA, CAREYNA H, ALTUS, CHRISTINA M, YU, JIMMY Y, GIETZEN, DARRYL, MARWAHA, RAKESH, CHALUP, MICHAEL S, GERSTIN, EDWARD H., JR, ROSEBERRY, ANN M, LINCOLN, STEPHEN E, FLORES, VINCENT, JONES, ANISSA LEE, CHANG, SIMON C
• Format: Patent
• Language: English; French
• Published: 23.05.2002
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPIRITS; TRAPPING; VINEGAR; WINE

The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT ) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. Th e invention further provides for vectors and host cells containing mddt for th e expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.