SECRETORY POLYPEPTIDES AND CORRESPONDING POLYNUCLEOTIDES

• Main Authors: YAP, PIERRE E, DANIELS, SUSAN E, BANVILLE, STEVEN C, ROSEN, BRUCE H, DAFFO, ABEL, HILLMAN, JENNIFER L, LIU, TOMMY F, WRIGHT, RACHEL J, PANZER, SCOTT R, STOCKDREHER, THERESA K, RUSSO, FRANK D, BRADLEY, DIANA L, DAHL, CHRISTOPHER R, AMSHEY, STEFAN, JONES, ANISSA L, BRATCHER, SHAWN R, DUFOUR, GERARD E, SHAH, PURVI, SPIRO, PETER A, CHEN, WENSHENG, COHEN, HOWARD J, CHEN, ALICE, YU, JIMMY Y, D'SA, STEVEN A, CHALUP, MICHAEL S, ROSEBERRY, ANN M, HODGSON, DAVID M, FONG, WILLY T, GREENAWALT, LILA B, LINCOLN, STEPHEN E, DAM, TAM C, FLORES, VINCENT, CHANG, SIMON C
• Format: Patent
• Language: English; French
• Published: 30.08.2001
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPIRITS; TRAPPING; VINEGAR; WINE

The present invention provides purified secretory polynucleotides (sptm). Al so encompassed are the polypeptides (SPTM) encoded by sptm. The invention also provides for the use of sptm, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing sptm for the expression of SPTM. The invention additionally provides for the use of isolated and purified SPTM to induce antibodies and to screen libraries of compounds and the use of anti-SPTM antibodies in diagnostic assays. Also provided are microarrays containing sp tm and methods of use.