NOVEL PIPERIDINE COMPOUND AND PHARMACEUTICAL THEREOF

Novel compounds having an excellent Na+ channel inhibiting activity, which a re compounds of the general formula (I), salts thereof, or hydrates of both, wherein A is a ring of the general formula (IA), (II) (wherein R1 is hydroge n or the like; and R2 is hydrogen or the like), or the like; W is opt...

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Main Authors KANEKO, TOSHIHIKO, ONOGI, TATSUHIRO, TABATA, MUTSUKO, TAKAHASHI, YOSHINORI, OHKUBO, MIYUKI, YOSHIDA, ICHIRO, KATO, KOJI, MATSUKURA, MASAYUKI, KAMATA, JUNICHI, YOSHINAGA, TADASHI, ISHIHARA, HIROKI, MIYAZAKI, KAZUKI, SAWADA, KOHEI, KOBAYASHI, KIYOAKI, OZAKI, FUMIHIRO, SUZUKI, HIROYUKI
Format Patent
LanguageEnglish
French
Published 26.07.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel compounds having an excellent Na+ channel inhibiting activity, which a re compounds of the general formula (I), salts thereof, or hydrates of both, wherein A is a ring of the general formula (IA), (II) (wherein R1 is hydroge n or the like; and R2 is hydrogen or the like), or the like; W is optionally substituted C1-6 alkylene or the like; Z is an optionally substituted C6-14 aromatic carbocyclic group or the like; and l is an integer of 0 to 6.</SDOA B>
Bibliography:Application Number: CA20012398388