NOVEL 1,8-NAPHTHYRIDIN-2(1H)-ONE DERIVATIVES

• Main Authors: NOSE, TAKASHI, AOTSUKA, TOMOJI, ISHITANI, KOUKI, KUMAZAWA, KENTAROU, WAGATSUMA, NAGATOSHI
• Format: Patent
• Language: English; French
• Published: 15.06.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Development of selective PDE IV inhibitors excellent in antiasthmatic activity, safety, and so on. Compounds of general formula (1) or pharmaceutically acceptable salts thereof exhibit a selective PDE IV inhibiting effect and are useful as drugs, particularly antiasthmatic agent; wherein A is an opt...