N-[2-HYDROXY-3-(1-PIPERIDINYL)PROPOXY]PYRIDINE-1-OXIDE-3-CARBOXIMIDOYL CHLORIDE AND ITS USE IN THE TREATMENT OF INSULIN RESISTANCE

The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts thereof, pharmaceutical compositions containing the same, the use of these compounds in the treatment of pathological insulin resistance, and for...

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Main Authors KOMAROMI, ANDRAS, KARDOS, MIHALYNE, NAGY, KAROLY, MARVANYOS, EDE, KURTHY, MARIA, UROGDI, LASZLO, NAGY, MELINDA, SZILBEREKY, JENO, CSAKAI, ZITA, MOGYOROSI, TAMAS, TOROK, MAGDOLNA, BIRO, KATALIN, KORANYI, LASZLO, BARABAS, MIHALY, NAGY, ZOLTAN
Format Patent
LanguageEnglish
French
Published 04.01.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts thereof, pharmaceutical compositions containing the same, the use of these compounds in the treatment of pathological insulin resistance, and for the treatment of pathological conditions associated therewith, for the treatment of pathological insulin resistance, and the treatment of pathological conditions associated therewith, by simultaneous treatment and prevention of diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy and/or with simultaneous increasing pathologically decreased peripheral neuroregeneration caused by diabetes and methods of treatment.
AbstractList The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts thereof, pharmaceutical compositions containing the same, the use of these compounds in the treatment of pathological insulin resistance, and for the treatment of pathological conditions associated therewith, for the treatment of pathological insulin resistance, and the treatment of pathological conditions associated therewith, by simultaneous treatment and prevention of diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy and/or with simultaneous increasing pathologically decreased peripheral neuroregeneration caused by diabetes and methods of treatment.
Author KOMAROMI, ANDRAS
MOGYOROSI, TAMAS
NAGY, ZOLTAN
SZILBEREKY, JENO
NAGY, MELINDA
UROGDI, LASZLO
TOROK, MAGDOLNA
KURTHY, MARIA
NAGY, KAROLY
KORANYI, LASZLO
BIRO, KATALIN
CSAKAI, ZITA
BARABAS, MIHALY
KARDOS, MIHALYNE
MARVANYOS, EDE
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– fullname: NAGY, KAROLY
– fullname: MARVANYOS, EDE
– fullname: KURTHY, MARIA
– fullname: UROGDI, LASZLO
– fullname: NAGY, MELINDA
– fullname: SZILBEREKY, JENO
– fullname: CSAKAI, ZITA
– fullname: MOGYOROSI, TAMAS
– fullname: TOROK, MAGDOLNA
– fullname: BIRO, KATALIN
– fullname: KORANYI, LASZLO
– fullname: BARABAS, MIHALY
– fullname: NAGY, ZOLTAN
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DocumentTitleAlternate CHLORURE DE N-[2-HYDROXY-3-(1-PIPERIDINYL)PROPOXY]PYRIDINE-1-OXYDE-3-CARBOXIMIDOYL ET SES UTILISATIONS DANS LE TRAITEMENT DE LA RESISTANCE A L'INSULINE
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Snippet The invention relates to N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers and the acid addition salts...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title N-[2-HYDROXY-3-(1-PIPERIDINYL)PROPOXY]PYRIDINE-1-OXIDE-3-CARBOXIMIDOYL CHLORIDE AND ITS USE IN THE TREATMENT OF INSULIN RESISTANCE
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