PROCESS FOR PREPARING 3-(HYDROXYMETHYL)CHROMEN-4-ONES

3-(Hydroxymethyl)chromen-4-ones of formula (I) are described and a process f or preparing said compounds. The process consists in reacting the compounds of general formula (II) wherein R is hydrogen, halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms optionally substitute...

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Main Authors SACRISTAN, AURELIO, FOGUET, RAFAEL, CASTELLO, JOSEP M, BOLOS, JORDI, ORTIZ, JOSE A
Format Patent
LanguageEnglish
French
Published 07.11.2006
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Summary:3-(Hydroxymethyl)chromen-4-ones of formula (I) are described and a process f or preparing said compounds. The process consists in reacting the compounds of general formula (II) wherein R is hydrogen, halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms optionally substituted by phenyl or halogen, with formaldehyde and a basic catalyst followed by dehydration in an acid medium to form 3-(hydroxymethyl)chromen-4-ones of general formula (I), where in R is as defined for (II).
Bibliography:Application Number: CA19992344664