N-(3-ETHYNYLPHENYL-6,7-BIS(2-METHOXYETHOXY)-4-QUINAZOLINAMINE MESYLATE ANHYDRATE AND MONOHYDRATE

The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods o...

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Bibliographic Details
Main Authors ALLEN, DOUGLAS JOHN MELDRUM, SANTAFIANOS, DINOS PAUL, RAGGON, JEFFREY WILLIAM, NORRIS, TIMOTHY, SHANKER, RAVI MYSORE
Format Patent
LanguageEnglish
French
Published 30.06.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods of treating hyperproliferative disorders, such as cancer, by administering N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- quinazolinamine mesylate.
Bibliography:Application Number: CA19992330447