RETROVIRAL DELIVERY SYSTEM

A retroviral delivery system capable of transducing a target site is described. The retroviral delivery system comprises a first nucleotide sequence coding for at least a part of an envelope protein; and one or more other nucleotide sequences derivable from a retrovirus that ensure transduction of t...

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Bibliographic Details
Main Authors ELLARD, FIONA MARGARET, MITRAPHANOUS, KYRIACOS ANDREOU, KINGSMAN, ALAN JOHN, KINGSMAN, SUSAN MARY, PATIL, DEVA
Format Patent
LanguageEnglish
French
Published 02.12.1999
Edition6
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Summary:A retroviral delivery system capable of transducing a target site is described. The retroviral delivery system comprises a first nucleotide sequence coding for at least a part of an envelope protein; and one or more other nucleotide sequences derivable from a retrovirus that ensure transduction of the target site by the retroviral delivery system; wherein the first nucleotide sequence is heterologous with respect to at least one of the other nucleotide sequences; and wherein the first nucleotide sequence codes for at least a part of a rabies G protein or a mutant, variant, derivative or fragment thereof that is capable or recognising the target site.
Bibliography:Application Number: CA19992328491