DIARYL-5-ALKYL-5-METHYL-2(5H)-FURANONES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS

The invention encompasses compounds of Formula (I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I), e.g. (5R)-3-(3,4-difluorophenyl)-5-ethyl-5-methyl-...

Full description

Saved in:
Bibliographic Details
Main Authors LEGER, SERGE, GRIMM, ERICH, WANG, ZHOAYIN
Format Patent
LanguageEnglish
French
Published 14.05.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The invention encompasses compounds of Formula (I) as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I), e.g. (5R)-3-(3,4-difluorophenyl)-5-ethyl-5-methyl-4-¢4-(methylsulfonyl)phenyl!-2,5-dihydro-2-furanone.
Bibliography:Application Number: CA19982307853