METHODS AND REAGENTS FOR IDENTIFYING MODULATORS OF NEURONAL APOPTOSIS

The invention provides assays for modulators of neuronal apoptosis. The assays include measurement of the levels of p53, Bad, Bax, p21, p27 and phosphorylated Rb in neurons which have been induced to undergo apoptosis.

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Bibliographic Details
Main Authors MILLER, FREDA DIANE, ALOYZ, RAQUEL SILVIA, KAPLAN, DAVID
Format Patent
LanguageEnglish
French
Published 04.03.1999
Edition7
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The invention provides assays for modulators of neuronal apoptosis. The assays include measurement of the levels of p53, Bad, Bax, p21, p27 and phosphorylated Rb in neurons which have been induced to undergo apoptosis.
Bibliography:Application Number: CA19982301795