ENHANCEMENT OF GENE EXPRESSION

A method for enhancing the expression of a selected gene in an organism while avoiding or reducing co-suppression involves the synthesis of a DNA which is altered in nucleotide sequence and is capable of expression of a protein, ideally identical to that of a protein already expressed by a DNA alrea...

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Bibliographic Details
Main Authors BIRD, COLIN ROGER, SCHUCH, WOLFGANG WALTER, DRAKE, CAROLINE RACHEL
Format Patent
LanguageEnglish
French
Published 11.12.1997
Edition6
Subjects
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Summary:A method for enhancing the expression of a selected gene in an organism while avoiding or reducing co-suppression involves the synthesis of a DNA which is altered in nucleotide sequence and is capable of expression of a protein, ideally identical to that of a protein already expressed by a DNA already present in the organism. This method ensures that sequence similarity between the two genes is reduced enough to eliminate the phenomenon of co-suppression, allowing the over-expression of a specific protein. The method is particularly suitable in plants.
Bibliography:Application Number: CA19972252366