AZAINDOLE-ETHYLAMINE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR BINDING AGENTS

Disclosed are compounds that are useful in the treatment of conditions associated with depletion of nicotine receptors in mammals, the compounds having formula I: (wherein X is; a) -CH2NR1R2; b) ; or c) ; where R, R1, and R2 are independently selected from hydrogen and C1-C6 alkyl; R3 is selected fr...

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Bibliographic Details
Main Author NAGEL, ARTHUR ADAM
Format Patent
LanguageEnglish
French
Published 09.10.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are compounds that are useful in the treatment of conditions associated with depletion of nicotine receptors in mammals, the compounds having formula I: (wherein X is; a) -CH2NR1R2; b) ; or c) ; where R, R1, and R2 are independently selected from hydrogen and C1-C6 alkyl; R3 is selected from hydrogen, halogen and C1-C6 alkyl; 1 is an integer from 0-4; m is in integer from 0-4; and n is an integer from 0-2); or pharmaceutically acceptable salts thereof.
Bibliography:Application Number: CA19982234567